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Eating well for healthy living: Examining the role of supplements

By Deanna Groetzinger and Josée Poirier
from MS Canada, May 2005, pp. 14-15

Healthy living with MS includes a healthy diet. Questions that sometimes arise are: what foods are best to stay healthy and do I need extra vitamins or food supplements?

Over the years, a wide variety of nutritional approaches have been suggested – some with little or no evidence that they do any good. However, it makes sense that a healthy approach to eating can keep the body in the best shape possible to facilitate repair and replacement of injured tissue, whether it is a “broken leg or damaged myelin”, pointed out Dr. Brenda Banwell, director of the Pediatric MS Clinic, Hospital for Sick Children, Toronto.

So what does this mean in practical terms when you go shopping? Many nutritionists recommend an overall diet that is high in vegetables and fruit, whole wheat grain products, lowfat dairy products, lean meats, poultry and fish. Foods that are high in animal fats and sugars should be avoided.

A healthy diet for people with MS is very much what is recommended by the Canada Food Guide with one exception. Increasingly, some nutritionists recommend that people with MS may want to include oily fish (tuna, salmon, sardines, mackerel) because they have high amounts of omega-3 oils. Vegetable oils (sunflower, safflower or soya oils), are also seen to be beneficial to overall health. They are naturally high in linoleic acid, a type of omega-6 oil.

The reasoning behind including these oils is that there is some indication they may be useful in slowing down the progression of MS, although this has not been confirmed.

Another question that arises frequently is whether food supplements or vitamins are useful in maintaining overall health or whether they might even have an effect on MS signs and symptoms.

Tips for using vitamins, food supplements and herbal remedies

  • Don’t take any product that stimulates your immune system.

  • Try only one new product at a time. If you haven’t experienced
    a change for the better after using it for four weeks, stop taking it.

  • Be careful about buying products over the Internet.

  • Be sure to tell your family doctor, neurologist and pharmacist what products you’re using.

  • Remember that there’s no such thing as a miracle drug.

  • Eat properly – if you eat enough fruits and vegetables, you shouldn’t need vitamins and food supplements.

  • If you do try a supplement, respect the recommended dosage.

Adapted from “Be careful with food supplements”, by Josée Poirier, R.N., in MS Quebec, December 2004.

Certainly food supplements are everywhere these days. You can’t turn on the TV or the radio without being bombarded by ads describing the spectacular effects of one product or another. But you have to be careful with both food supplements and vitamins.

“It’s important to remember that ‘natural or herbal’ does not mean without side effects,” said Dr. Banwell. Some products actually stimulate the immune system which could become a problem in MS, which results because of a misdirected immune attack on myelin within the central nervous system. In addition, they can conflict with other medications and, it is also important to remember that food supplements are not regulated by Health Canada.

Following are some examples of common vitamins, supplements and herbal therapies and their pros and cons.

Vitamin D

Vitamin D has been recognized by MS researchers as possibly being helpful in preventing MS. Many physicians now suggest that people with MS themselves might benefit from taking vitamin D. The current official Canadian recommendation is 400 IU of vitamin D daily. Many MS specialists suggest that a daily intake of 800 – 1,000 IU of vitamin D is safe – because some people with MS may be vitamin D deficient.

Coenzyme Q10 or ubiquinone

Q10 is an antioxidant that may have a neuroprotective effect, which could be beneficial for MS. On the other hand, Q10 also stimulates the immune system, which represents a risk for people with MS.

Echinacea

Echinacea purpurea or purple coneflower is used by many people to treat colds and flu, however, it should be avoided by people with MS since it stimulates the immune system, which is risky. In addition, echinacea may reduce the effects of the disease modifying drugs such as the interferons and glatiramer acetate and may increase the risk of high levels of liver enzymes (hepatotoxicity) if combined with methotrexate (an immune suppressing drug) or the interferons.

Noni juice

This juice is from the fruit of a Polynesian plant (Morinda citrifolia). While ads claim it is effective in treating MS, no scientific studies have confirmed this. In addition noni juice contains polysaccharides that some studies have shown to have a stimulating effect on the immune system – again this is a risk for people with MS. It can also reduce the effectiveness of the immunesuppressing drugs or the disease modifying therapies.

St. John’s wort

A widely available herbal medicine, St. John’s wort (Hypericum perforatum) appears to be effective at treating mild to moderate depression. However, people with MS should note that it has sedative properties that may aggravate fatigue or increase the sedative effect of drugs used to treat spasticity such as baclofen, Zanaflex (tizanidine) and amitriptyline. St. John’s wort can also interact with antidepressants, anticonvulsants and birth control pills. It should be avoided by anyone who is already taking an antidepressant and by pregnant women and nursing mothers. People with MS who are thinking about trying a food supplement, vitamin or herbal remedy, should always talk to their physician or pharmacist before trying a new product. It is vital to ensure there is no interaction with any medication you are already taking.

Tips for healthy eating

  • Choose low-fat dairy products, such as low-fat yogurt and semi-skimmed milk.

  • Eat oily fish, such as tuna, salmon or mackerel, two or three times weekly.

  • Choose chicken, turkey and leaner cuts of red meat.

  • Grill, bake, steam or poach foods instead of frying.

  • Use omega-6 vegetable oil or spreads in moderate amounts. These include sunflower, safflower and soya products.

  • Avoid the animal fats contained in pastry, pies, cakes, chocolate and cream.

  • Eat whole grain bread and cereals.

  • Eat at least five portions of fruit and vegetables daily.

  • Drink two litres or more of sugar-free fluids daily.

Adapted from “Making nutritional choices”, MS in Focus, Healthy Living, Issue 5, 2005, published by MS International Federation. Available at www.msif.org

At the time of this article (May 2005) Deanna Groetzinger was National Vice-President, Communications, MS Society of Canada; Josée Poirier was Coordinator, MS Clinic, Notre Dame Hospital, Montreal.


Additional resources

Healthy Eating, available from MS Society of Canada offices or at www.mssociety.ca.

Dietary Supplements and Multiple Sclerosis: A Health Professional’s Guide by Allen C. Bowling, M.D., Ph.D., and Thomas M. Stewart, I.D., P.A.C.; Demos Medical Publishing. (Available at www.demosmedpub.com or check your local bookstore.)

Canada Food Guide, available at www.hc-sc.gc.ca under Healthy Living/Food and Nutrition; or call Health Canada at (613) 954-5995.

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