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Types of MS

Multiple sclerosis is grouped into several main types. These include:

Clinically Isolated Syndrome

The earliest form of MS. There is a single attack of neurological symptoms, but often multiple lesions are seen on the brain MRI.

Relapsing-Remitting MS (RRMS)

Characterized by clearly defined attacks (relapses) followed by complete or partial recovery (remissions); most common form (75% at the time of diagnosis).
Graph of Relapsing-Remitting MS (RRMS). It is characterized by clearly defined attacks (relapses) followed by complete or partial recovery (remissions); most common form (75% at the time of diagnosis).

Benign MS

A sub-type of RRMS in which remission after relapses is almost complete, so that 10-15 years after the onset of the disease, there is still only minimal disability. Ten to fifteen per cent of all cases of MS are benign. In most cases of benign MS, the symptoms mainly affect the senses of sight and/or touch. The proportion of people with MS who still have benign MS decreases with time, from 60% after 10 years, to 40% after 20 years, and to 25% after 30 years.

Progressive MS

Disability slowly and continuously increases with or without relapses.

Primary-progressive MS

Less common (10 to 15% at time of diagnosis), people with this type of MS have a nearly continuous worsening of MS from the beginning with no clear relapses or remissions. Primary progressive MS generally appears in people in their forties, and it is the only form of MS that affects men and women equally.
Graph of primary-progressive MS. People with this type of MS have a nearly continuous worsening of MS from the beginning with no clear relapses or remissions.

Secondary-progressive

The disease becomes progressive after an initial relapsing-remitting phase. Eventually (after 5-25 years or more) more people with relapsing-remitting MS develop secondary progressive MS. In this type of MS, the disease will progress with or without relapses. When attacks do occur, the recovery is usually not complete; so disability then accumulates over time.
Graph of secondary-progressive MS becomes progressive after an initial relapsing-remitting phase. will progress with or without relapses. When attacks do occur, the recovery is usually not complete; so disability then accumulates over time.

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